Research progress in low-dose radiotherapy for osteoarthropathy
10.3760/cma.j.cn113030-20230310-00043
- VernacularTitle:骨关节病低剂量放射治疗的研究进展
- Author:
Yang FENG
1
;
Zengwei HAN
;
Yuan YAO
;
Dong LI
Author Information
1. 上海交通大学医学院附属第九人民医院放疗科，上海 201999
- Keywords:
Osteoarthropathy;
Low-dose radiotherapy;
Research progress
- From:
Chinese Journal of Radiation Oncology
2024;33(3):269-274
- CountryChina
- Language:Chinese
-
Abstract:
Osteoarthropathy is a common chronic disease among middle-aged and elderly populations, characterized by joint pain, limited mobility, and even disability in severe cases. Treatment methods include weight control, functional exercise, local or systemic medication use, and ultimately joint replacement surgery. However, patients often experience ineffective drug treatment or inability to tolerate adverse drug reactions, as well as inability to tolerate joint replacement surgery. Multiple studies have shown that low-dose radiotherapy can alleviate joint pain and limited mobility by regulating multiple stages of the inflammatory process. In addition, the risk of secondary malignant tumors is extremely low, with rare acute and chronic adverse reactions. However, there is still some controversy regarding the optimal segmentation method for radiotherapy in clinical applications, which remains to be elucidated by more prospective studies. Low-dose radiotherapy for osteoarthropathy has been rarely studied in China. This non-invasive, safe, and effective treatment is expected to provide more treatment options for Chinese patients with osteoarthritis.
