Research progress in preoperative stereotactic radiosurgery for resectable brain metastases
10.3760/cma.j.cn113030-20230210-00025
- VernacularTitle:可切除脑转移瘤术前立体定向放射外科的研究进展
- Author:
Xuefang ZHANG
1
;
Jiefang HE
;
Yuanyuan CHEN
Author Information
1. 广东医科大学，湛江 524000
- Keywords:
Neoplasm metastasis, brain;
Neoplasms/surgery;
Stereotactic radiosurgery;
Preoperative treatment
- From:
Chinese Journal of Radiation Oncology
2023;32(12):1093-1098
- CountryChina
- Language:Chinese
-
Abstract:
Surgery combined with postoperative stereotactic radiosurgery (SRS) can improve the overall survival and becomes one of main treatments for resectable brain metastases. Compared with postoperative SRS, preoperative SRS (Pre-SRS) has theoretical advantages of reducing the dissemination of active tumor cells into the treatment cavity during surgery, reducing radiation dose, reducing radiation to surrounding normal brain tissue, and ensuring successful implementation of perioperative treatment, etc. Recent clinical studies have confirmed that Pre-SRS can reduce local recurrence rate and the incidence of radiation necrosis (RN) and leptomeningeal metastasis (LMM). Moreover, the indications, dose fractionation, and combined therapy remain to be confirmed by more prospective studies. In this article, research progress in Pre-SRS for resectable brain metastases was reviewed.
