Advances in clinical research of boron neutron capture therapy
10.3760/cma.j.cn113030-20220915-00307
- VernacularTitle:硼中子俘获治疗的临床研究进展
- Author:
Huanyu ZHANG
1
;
Pengcheng ZHANG
;
Youzhe ZHU
;
Juntao RAN
Author Information
1. 兰州大学第一医院放疗科，兰州 730000
- Keywords:
Neoplasms;
Radiotherapy;
Boron neutron capture therapy;
Research progress
- From:
Chinese Journal of Radiation Oncology
2023;32(9):848-853
- CountryChina
- Language:Chinese
-
Abstract:
Boron neutron capture therapy (BNCT) is an advanced method of precision radiotherapy for tumors. In BNCT, 10B enriched boron carriers enter and gather within tumor cells, then a thermal neutron beam triggers the 10B (n, α) 7Li reaction to release alpha and 7Li particle with low energy, which can kill tumor cells. Compared with conventional radiotherapy, BNCT has the characteristics of higher biological effect, more precise targeting, less damage to normal tissues and less treatment times. In this article, recent progress and existing problems of BNCT-related clinical research were reviewed.
