Prosthetic Valve Endocarditis caused by HACEK Organisms: a Case Report and Systematic Review of the Literature.

Author: Ha Na CHOI ¹ ; Ki Ho PARK ; Soyoung PARK ; Jae Min KIM ; Hyun Joon KANG ; Jae Hun PARK ; Mi Suk LEE
Author Information

1. Department of Internal Medicine, Kyung Hee University Hospital, Kyung Hee University School of Medicine, Seoul, Korea. mslee@khmc.or.kr
Publication Type:Case Report
Keywords: HACEK; Aggregatibacter aphrophilus; Endocarditis; Heart valve prosthesis
MeSH: Adult; Aggregatibacter aphrophilus; Endocarditis*; Heart Valve Prosthesis; Humans; Male; Recurrence
From:Infection and Chemotherapy 2017;49(4):282-285
CountryRepublic of Korea
Language:English
Abstract: HACEK is a rare cause of prosthetic valve endocarditis (PVE). We describe 42-year-old male patient who presented with Aggregatibacter aphrophilus PVE and cerebral infarct. A. aphrophilus was isolated from his blood cultures as the sole pathogen, which was confirmed by subsequent 16S rRNA sequencing. He was treated with valve replacement surgery and an 8 week course of pathogen-directed antibiotic therapy and followed for 20 months without recurrence.