Study on TCM Syndromes of Advanced Gastric Cancer Based on Principal Component Analysis and Clustering Analysis
10.19879/j.cnki.1005-5304.202304177
- VernacularTitle:基于主成分分析与聚类分析的进展期胃癌中医证候研究
- Author:
Jiaxin GUO
1
;
Qianru YANG
;
Dong YAN
;
Qing DONG
Author Information
1. 北京急救中心,北京 100031
- Keywords:
advanced gastric cancer;
TCM syndromes;
principal component analysis;
clustering analysis
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2024;31(4):153-156
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the characteristics and distribution of TCM syndromes of advanced gastric cancer;To provide reference for the standardization and clinical research of TCM syndromes of advanced gastric cancer.Methods The four diagnosis information with advanced gastric cancer was retrospectively collected at Dongzhimen Hospital of Beijing University of Chinese Medicine from January 2010 to December 2020.And the investigation results were analyzed by combining principal component analysis and clustering analysis,so as to explore the distribution pattern of TCM syndromes of advanced gastric cancer.Results Totally 164 patients were included,involving 601 case-times.10 principal components were obtained through principal component analysis on 29 items of four diagnosis information.The four diagnosis information with factor coefficient>0.4 were selected and allocated to the 10 principal components.Then,based on the results of principal component analysis,clustering analysis was conducted to obtain the distribution proportion of the three types of TCM syndromes.According to the syndrome differentiation by professional clinicians,the results were followed by the frequency distribution as cold coagulation and blood stasis(356,59.28%),stomach yin deficiency(145,24.17%)and phlegm-heat accumulation(100,16.55%).Conclusion There are three basic TCM syndromes of advanced gastric cancer,which are cold coagulation and blood stasis,stomach yin deficiency and phlegm-heat accumulation.Cold coagulation and blood stasis occupies the largest proportion,and the treatment should be based on warming the middle to dissipate cold and promoting blood circulation to remove blood stasis.
