Exploration on the Biological Implications of"Earth Deficiency and Wood Depression"Pathogenesis of Hypertension from Intestinal Flora-bile Acid Axis
10.19879/j.cnki.1005-5304.202302054
- VernacularTitle:从肠道菌群-胆汁酸轴探讨高血压"土虚木郁"病机的生物学内涵
- Author:
Meilong SI
1
;
Hua JIN
;
Minke LIU
;
Yu WANG
;
Qiuju ZHANG
;
Shuangfang LIU
;
Bishi LING
;
Shangwen QI
Author Information
1. 甘肃中医药大学,甘肃 兰州 730000
- Keywords:
intestinal flora-bile acid axis;
earth deficiency and wood depression;
hypertension
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2024;31(3):13-18
- CountryChina
- Language:Chinese
-
Abstract:
There is a bidirectional relationship between intestinal flora and bile acids,and the imbalance of intestinal flora-bile acid axis metabolism is closely related to hypertension.Based on classical TCM literature and clinical practice,this article found that"earth deficiency"is the important pathological basis of hypertension,"wood depression"is the initiating factor of hypertension,and"earth deficiency and wood depression"is the key pathogenesis of hypertension.Combined with the research results of modern medicine and molecular biology,it is considered that the imbalance of intestinal flora and abnormal bile acid metabolism are closely related to the"earth deficiency"and"wood depression"of TCM respectively,and the imbalance of intestinal flora-bile acid axis coincides with the"earth deficiency and wood depression"of TCM in the process of hypertension.It is of great theoretical and practical significance to explore the biological connotation of hypertension"earth deficiency and wood depression"from the perspective of intestinal flora-bile acid axis for guiding TCM to prevent and treat hypertension.
