Exploration on Characteristics of Acupoint Efficacy Based on the Self-developed ACU&MOX-DATA Platform
10.19879/j.cnki.1005-5304.202303269
- VernacularTitle:基于自主研发ACU&MOX-DATA平台探索腧穴功效特点研究
- Author:
Sihui LI
1
,
2
;
Shuqing LIU
;
Qiang TANG
;
Ruibin ZHANG
;
Wei CHEN
;
Hao HONG
;
Bingmei ZHU
;
Xun LAN
;
Yong WANG
;
Shuguang YU
;
Qiaofeng WU
Author Information
1. 成都中医药大学针灸推拿学院,四川 成都 610075
2. 成都中医药大学针灸与内稳态研究所,四川 成都 610075
- Keywords:
acupoint efficacy;
interventions of acupuncture and moxibustion;
target organ response;
multi-omics data;
heterogeneous data analysis
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2024;31(2):64-69
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effects of different acupoints,different target organs,and different interventions on acupoint efficacy based on ACU&MOX-DATA platform;To illustrate and visualize whether the above factors have the characteristics of"specific effect"or"common effect"of acupoint efficacy.Methods The multi-source heterogeneous data were integrated from the original omics data and public omics data.After standardization,differential gene analysis,disease pathology network analysis,and enrichment analysis were performed using Batch Search and Stimulation Mode modules in ACU&MOX-DATA platform under the conditions of different acupoints,different target organs,and different interventions.Results Under the same disease state and the same intervention,there were differences in effects among different acupoints;under the same disease state,the same acupoint and intervention,the responses produced by different target organs were not completely consistent;under the same disease state and acupoint,there were differences in effects among different intervention measures.Conclusion Based on the analysis of ACU&MOX-DATA platform,it is preliminary clear that acupoints,target organs,and interventions are the key factors affecting acupoint efficacy.Meanwhile,the above results have indicated that there are specific or common regulatory characteristics of acupoint efficacy.Applying ACU&MOX-DATA platform to analyze and visualize the critical scientific problems in the field of acupuncture and moxibustion can provide references for deepening acupoint cognition,guiding clinical acupoint selection,and improving clinical efficacy.
