Research Progress in TCM for Prevention and Treatment of Precancerous Lesions of Gastric Cancer Based on Angiogenesis Microenvironment
10.19879/j.cnki.1005-5304.202212116
- VernacularTitle:中药基于血管生成微环境防治胃癌前病变研究进展
- Author:
Zhuangzhuang FENG
1
;
Pengcheng DOU
;
Ruiping SONG
;
Xinyi CHEN
;
Juan'e WANG
;
Ruirui GAO
;
Xiaolong WANG
;
Jin SHU
Author Information
1. 甘肃中医药大学,甘肃 兰州 730000
- Keywords:
precancerous lesions of gastric cancer;
angiogenesis microenvironment;
TCM treatment;
review
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2024;31(1):180-184
- CountryChina
- Language:Chinese
-
Abstract:
The angiogenic microenvironment is a new blood vessel with different molecular and functional characteristics that sprouts on the original blood vessels through different mechanisms,which directly affects the process of tumor cell growth,proliferation,and migration and has an important impact on the occurrence and development of precancerous lesions of gastric cancer.Correa mode has shown that precancerous lesions of gastric cancer is the key pathological stage before the occurrence of gastric cancer,and it is of great significance to advance the prevention and treatment strategy to this stage.TCM believes that qi deficiency and blood stasis is the key pathogenesis of precancerous lesions of gastric cancer,and its basic treatment is to replenish qi and remove blood stasis,and based on the syndrome differentiation,drugs with the efficacy of nourishing yin and tonifying stomach,soothing the liver and regulating qi,resolving phlegm and dispersing lumps,and clearing heat and dampness for treatment.This article discussed the correlation between precancerous lesions of gastric cancer and angiogenic microenvironment and its regulatory pathways,and summarized the methods and mechanisms of TCM in the treatment of precancerous lesions of gastric cancer from the perspective of regulating angiogenic microenvironment-related pathways,in order to provide a reference for the treatment of precancerous lesions of gastric cancer with TCM.
