Clinical Study on the Effects of Yiweining Capsules Combined with Rebamipide Tablet in Treating Chronic Atrophic Gastritis with Spleen-stomach Qi Deficiency Syndrome
10.19879/j.cnki.1005-5304.202302440
- VernacularTitle:益胃宁胶囊联合瑞巴派特片治疗慢性萎缩性胃炎脾胃气虚证临床研究
- Author:
Chunrong YE
1
;
Youcheng HE
;
Shuihua TANG
;
Jinxian YAN
Author Information
1. 福建中医药大学附属第二人民医院,福建 福州 350003
- Keywords:
Yiweining Capsules;
chronic atrophic gastritis;
spleen-stomach qi deficiency syndrome;
clinical efficacy
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2024;31(1):142-146
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the clinical effects of Yiweining Capsules combined with rebamipide tablet in the treatment of spleen-stomach qi deficiency syndrome in chronic atrophic gastritis(CAG).Methods Totally 80 patients with CAG were divided into the study group and the control group by using the random number table method,with 40 cases in each group.Both groups were given rebamipide tablet,0.1 g/time,3 times a day,orally;on this basis,the study group added Yiweining Capsules 2 g/time,3 times a day,orally.Both groups were treated continuously for 12 weeks.The TCM efficacy,the efficacy of gastroscopy and the efficacy of histopathology in the two groups were observed.The TCM symptom score before and after treatment in two groups were observed.The adverse reactions were recorded.Results No cases fell off in both groups.The total effective rate was 92.5%(37/40)in the study group and 70.0%(28/40)in the control group,and the clinical efficacy of the study group was better than that of the control group(P<0.01).Compared with before treatment,the total TCM symptom scores in the two groups after treatment decreased(P<0.01);Compared with after treatment,the total scores of TCM symptom in the study group were lower than those in the control group(P<0.05,P<0.01).The total effective rate of gastroscopy in the study group(82.5%)was better than that in the control group(67.5%),with statistical significance(P<0.05).The overall efficacy rate of histopathdogy in the study group(87.5%)was better than that of the control group(70.0%),with statistical significance(P<0.01).There were no adverse reactions in both groups.Conclusion Yiweining Capsules combined with rebamipide tablet can effectively improve the clinical symptoms,gastroscopic manifestations and the degree of mucosal lesions in patients with CAG,with remarkable efficacy.
