Exploration on Syndrome Differentiation Thinking for Stress Sensitization-induced Depression from the Perspective of"Deficient Qi with Stagnation and Heat"
10.19879/j.cnki.1005-5304.202308347
- VernacularTitle:从"虚气留滞夹火"探讨应激敏化所致抑郁症辨治思路
- Author:
Xu CHEN
1
;
Jing CAO
;
Qianlin JIA
;
Lingyun XI
;
Yang BAI
;
Haoyu PANG
;
Xia HONG
Author Information
1. 北京中医药大学,北京 100029
- Keywords:
depression;
stress sensitization;
deficient qi with stagnation and heat;
tonifying deficiency,promoting circulation,and clearing heat
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2024;31(1):11-14
- CountryChina
- Language:Chinese
-
Abstract:
TCM proposes that the core pathological mechanism of depression is"deficient qi with stagnation and heat",with the following pathogenic characteristics and evolution patterns:"deficient qi"as the nature,and deficiency in nature is in spleen,and deficiency in superficiality is in brain;"stagnation"is the superficiality,and qi stagnation,phlegm stagnation,and blood stagnation are in the brain collaterals;"heat"fires the brain collaterals,depression raised the heat,and excessive heat accumulated to stagnation.Based on the understanding of the pathogenesis of depression caused by stress sensitization in modern medicine,this article explored the potential association between this mechanism and the core pathogenesis of"deficient qi with stagnation and heat".It proposed that tonifying deficiency,promoting circulation,and clearing heat are the basic treatment principles for depression.By inhibiting inflammatory reactions and improving the stress sensitization state of neurons and glial cells,TCM compound formulas can exert multi-target and multi-dimensional therapeutic characteristics.
