Research progress on inflammation and endometrial receptivity
10.3760/cma.j.cn101721-20230927-00083-1
- VernacularTitle:炎症与子宫内膜容受性的研究进展
- Author:
Liyan WANG
1
;
Yuanyuan GAO
;
Mingxia GAO
Author Information
1. 兰州大学第一临床医学院,兰州 730000
- Keywords:
Endometrial receptivity;
Inflammation;
Embryo implantation
- From:
Clinical Medicine of China
2024;40(2):152-156
- CountryChina
- Language:Chinese
-
Abstract:
Inflammation is a key player in various pathophysiological processes and diseases, especially throughout the gestational cycle, and inflammation plays an important role in ovulation, embryo implantation, placental formation, and all stages of pregnancy maintenance. However, excessive inflammatory activity can impair endometrial receptivity, which can lead to clinical problems such as infertility, recurrent implantation failure, and recurrent miscarriage, which in turn can negatively impact women's reproductive health and pregnancy outcomes. Studies have shown that about two-thirds of embryo implantation failures are associated with inadequate endometrial receptivity. Therefore, the precise regulation of inflammatory states is of great significance for increasing pregnancy rates and improving pregnancy outcomes.