Role and new progress of AGP in pulmonary diseases and different systems diseases
10.3760/cma.j.cn101721-20230814-00021
- VernacularTitle:α1酸性糖蛋白在肺部疾病及不同系统疾病中的作用及新进展
- Author:
Ruiqi QIAN
1
;
Lingyi YANG
;
Xurui SHEN
;
Xiuqin ZHANG
;
Jian'an HUANG
Author Information
1. 苏州大学附属第一医院呼吸与危重症医学科，苏州 215006
- Keywords:
Alpha1-acid glycoprotein;
Pulmonary diseases;
Chronic obstructive pulmonary disease
- From:
Clinical Medicine of China
2024;40(1):73-76
- CountryChina
- Language:Chinese
-
Abstract:
Alpha1-acid glycoprotein (AGP), also known as oral mucus protein (ORM), is an acute phase positive protein. AGPs have various biological activities, such as drug transport, immune regulation, maintenance of capillary barrier, regulation of lipid metabolism, etc. AGP mainly exists in liver cells, but it is also expressed in other tissue cells, such as adipose tissue, brain tissue, endothelial cells and immune cells. This article mainly reviews the application of AGP in pulmonary diseases, and the role,significance and related new developments in different systemic diseases.
