Headache as the First Symptom of Mixed Phenotype (B-lymphocytic/myeloid) Acute Leukemia: A Case Report
10.3760/cma.j.cn101721-20230819-00032
- VernacularTitle:以头痛为首发表现的B淋系/髓系混合表型急性白血病1例并文献复习
- Author:
Aijun FENG
1
;
Shizao FEI
;
Zongsheng CHEN
;
Liuyi LUO
;
Jiatang ZHANG
Author Information
1. 华东师范大学附属芜湖医院 芜湖市第二人民医院神经内科，芜湖 241000
- Keywords:
Acute leukemia, mixed-phenotype;
Headache;
Initial symptom
- From:
Clinical Medicine of China
2023;39(6):466-470
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the clinical characteristics and complementary tests of a Chinese patient with central mixed phenotype acute leukemia and improve the awareness and diagnosis of MPAL among clinicians.Methods:Retrospectively analyzed a patient's clinical feature, laboratory examination, diagnosis and literature review who had headache as the first symptom and finally diagnosed with MPAL.Results:A 59-year-old female presented with recurrent headaches and can not relieved, at last , was confirmed as mixed phenotype acute leukemia by flow cytometry of cerebrospinal fluid、immunophenotyping and molecular biology of bone marrow. Remission was achieved after chemotherapy for lymphoid and myeloid leukemia.Conclusion:Patients with an unclear diagnosis of central nervous system disease, leukemia should be considered, and cerebrospinal fluid flow cytology and bone marrow biopsy should be refined.
