A case of multisystem inflammatory syndrome in children and literature review
10.3760/cma.j.cn101721-20230406-000131
- VernacularTitle:儿童多系统炎症综合征1例并文献复习
- Author:
Weijie LI
1
;
Ronghao ZHENG
;
Zhi XIA
;
Xiaolin WU
Author Information
1. 湖北医药学院 湖北省妇幼保健院培养基地，武汉 430070
- Keywords:
Multisystem inflammatory syndrome in children;
Kawasaki disease;
Children
- From:
Clinical Medicine of China
2023;39(5):351-357
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To improve clinicians' understanding of Multisystem Inflammatory Syndrome in Children (MIS-C) and to reduce missed and misdiagnosis.Methods:The clinical data of a patient with Multisystem inflammatory syndrome in children admitted to Maternal and Child Health Hospital of Hubei Province, Tongji Medical College, Huazhong University of Science and Technology in January 2023 were analyzed retrospectively, together with literature review.Results:A 10-year-old male patient was admitted to hospital with a fever for 5 days. This patient had a history of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection 1 month prior to admission; after admission, he continued to have recurring high fevers, accompanied by abdominal pain and Kawasaki disease like manifestations, shock, multiple organ function impairment, and a significant increase in inflammatory indicators. Finally, the patient was diagnosed with MIS-C, treated with intravenous immunoglobulin, glucocorticoids and aspirin, and discharged with clinical improvement.Conclusion:MIS-C was a novel syndrome with Kawasaki-like manifestations.Currently, the overall prognosis for MIS-C is good, but its pathogenesis is unclear and the therapeutic consensus remains limited. More studies are needed to clarify the best diagnosis and treatment methods and true prognosis.
