Analysisi of 145 clinical cases of sepsis in Tianjin Children's Hospital
10.3760/cma.j.cn101721-20230512-000181
- VernacularTitle:天津市儿童医院145例脓毒症临床病例分析
- Author:
Junting QIN
1
;
Wenshuang ZHANG
Author Information
1. 天津市儿童医院重症医学科，天津 300074
- Keywords:
Sepsis;
Child;
Biomarker;
Early recognization;
Death risk factors
- From:
Clinical Medicine of China
2023;39(5):321-326
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the clinical characteristics of hospitalized children with sepsis in the Department of Internal Medicine of Tianjin Children's Hospital, and explore the independent risk factors affecting the death of children with sepsis, so as to provide a basis for clinicians to identify, intervene and judge the prognosis of children with sepsis early.Methods:145 septic children (excluding newborns) who were hospitalized in the Department of Internal Medicine of Tianjin Children's Hospital from August 2016 to July 2019 were analyzed. Clinical data was collected through the electronic medical record system to analyze the characteristics of sepsis in these patients and to conduct regression analysis on the risk factors related to death of children with sepsis.Results:A total of 145 sepsis cases were enrolled in this study. Urinary tract infection accounted for 39.3% (57/145), ranking first in the infection site of medical sepsis. There were nine deaths in the study, eight of which had underlying medical conditions. The relevant risk factors of death cases were analyzed, and Logistic regression analysis showed that thrombocytopenia was an independent risk factor affecting the outcome of the disease ( OR=0.991, 95% CI, 0.983~0.998, P=0.019). Conclusions:The characteristics of children hospitalized with sepsis from August 2016 to July 2019 in the department of internal medicine of Tianjin Children's Hospital are as follows: The most common site of infection in the internal department of pediatric sepsis is urinary system infection, which is more common in patients with urinary malformations. Eight of the nine medical deaths had underlying medical conditions. Thrombocytopenia is an independent risk factor for death in patients with sepsis.
