Study on the application value of four-dimensional ultrasound combined with maternal serological screening in fetal facial deformities
10.3969/j.issn.1672-8270.2024.01.019
- VernacularTitle:四维超声联合母体血清学在胎儿颜面部畸形筛查中的价值研究
- Author:
Cun CHEN
1
;
Bingbing WANG
;
Lifei LIN
;
Chuiwan CHEN
Author Information
1. 上海交通大学医学院附属上海儿童医学中心海南医院超声电生理科 三亚 572000
- Keywords:
Four-dimensional ultrasound;
Maternal serology;
Fetal facial deformities
- From:
China Medical Equipment
2024;21(1):93-96
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the application value of four-dimensional ultrasound combined with maternal serological screening in fetal facial deformities.Methods:A total of 106 pregnant women at mid pregnancy,whose fetuses with suspected fetal facial deformities and who conducted prenatal screening in Sanya Maternal and Child Health Hospital(Sanya Women and Children's Hospital)from January 2020 to December 2022,were selected.All of them underwent four-dimensional ultrasound and maternal serological screening.The results of delivery or induced labor were used as the gold standard of diagnosis to compare the diagnostic values of single four-dimensional ultrasound,single maternal serological screening and the combination of them for fetal facial deformities.Results:The analysis of the receiver operating characteristic(ROC)curve showed that the area under curve(AUC)values of four-dimensional ultrasound,maternal serological screening and the combination of them were respectively 0.932,0.863 and 0.981 in diagnosing fetal facial deformities.Both the sensitivities and accuracies of four-dimensional ultrasound and maternal serological screening were significantly lower than those of the combined diagnosis of them in diagnosing fetal facial deformities,and the differences of them were statistical significance(x2=11.173,0.064,P<0.05),respectively.Conclusion:Four-dimensional ultrasound combines with maternal serological screening can improve the diagnostic accuracy for fetal facial deformities.
