Contrast-Enhanced Ultrasound in Assessing the Blood Perfusion of Kidney in Type 2 Diabetic Nephropathy
10.3969/j.issn.1005-5185.2024.03.015
- VernacularTitle:超声造影评估2型糖尿病肾病肾脏血流灌注的价值
- Author:
Weiwei YANG
1
;
Yiru WANG
;
Ping ZHAO
;
Nan LI
;
Qing SONG
;
Yukun LUO
;
Yuexiang WANG
Author Information
1. 解放军总医院第一医学中心超声诊断科,北京 100853
- Keywords:
Diabetic nephropathies;
Diabetes mellitus,type 2;
Glomerulosclerosis,focal segmental;
Glomerulosclerosis;
Ultrasonography;
Contrast media;
Blood perfusion
- From:
Chinese Journal of Medical Imaging
2024;32(3):284-288
- CountryChina
- Language:Chinese
-
Abstract:
Purpose To explore the clinical value of quantitative assessment of renal perfusion using ultrasound contrast imaging for the auxiliary diagnosis of type 2 diabetic nephropathy.Materials and Methods This prospective study was conducted from May 2017 to December 2019 at the First Medical Center of Chinese PLA General Hospital.A total of 41 patients with type 2 diabetes and renal function abnormalities,who were scheduled for renal biopsy,underwent contrast-enhanced ultrasound.Differences in contrast imaging parameters,including time to peak in the renal cortex,peak enhancement,mean transit time local,and area under the curve between diabetic nephropathy and focal segmental glomerulosclerosis were compared,and the correlation between imaging parameters and pathological results was analyzed.Results Among 41 patients,30 cases were diagnosed as diabetic nephropathy,and 11 cases were diagnosed as focal segmental glomerulosclerosis.The peak enhancement and area under the curve in the diabetic nephropathy group were significantly lower than those in the focal segmental glomerulosclerosis group[peak enhancement:3 837.16(2 449.16,5 929.16)vs.8 508.00(4 334.88,21 201.00),Z=-2.766,P=0.006;area under the curve:0.14±0.05 vs.0.19±0.05,t=-3.135,P=0.003].In the diabetic nephropathy group,peak enhancement showed a negative correlation with the global glomerulosclerosis rate(r=-0.489,P=0.006).Conclusion Contrast-enhanced ultrasound can quantitatively evaluate renal perfusion and has certain clinical value in assisting the diagnosis of type 2 diabetic nephropathy.
