Characteristics and Prognosis after Resection for Ruptured Hepatocellular Carcinoma.
- Author:
Jae Hyung BAE
1
;
Seong Woo HONG
;
Tae Gil HEO
;
Hyucksang LEE
Author Information
1. Department of Surgery, Seoul Paik Hospital, Inje University, Seoul, Korea. hyuckslee@gmail.com
- Publication Type:Original Article
- Keywords:
Hepatocellular carcinoma;
Spontaneous rupture;
Prognosis
- MeSH:
Carcinoma, Hepatocellular*;
Child;
Humans;
Leukocytosis;
Liver;
Portal Vein;
Postoperative Complications;
Prognosis*;
Recurrence;
Retrospective Studies;
Rupture;
Rupture, Spontaneous;
Survival Rate;
Thrombosis
- From:Korean Journal of Hepato-Biliary-Pancreatic Surgery
2006;10(3):37-41
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: A spontaneous rupture is a rare but life-threatening complication in patients with a hepatocellular carcinoma (HCC). Whether this condition has any influence on the subsequent outcome following a resection is unclear. Therefore, the long-term results of liver resection were compared in patients with and without a tumor rupture. METHOD: This retrospective study was conducted on 17 patients with a spontaneous rupture of an HCC out of 256 with an HCC who underwent hepatic resection. RESULTS: Reduced hemoglobin and albumin, as well as increased leukocytosis, a poor Child Class, large tumor and portal vein tumor thrombosis were more frequent clinical findings in patients with a ruptured HCC. The postoperative complication and extrahepatic recurrence rates were similar between the two groups. The 1- and 3- year survival rates in the 17 patients with a ruptured HCC were 41.2 and 17.7%, respectively, while these were 80.3 and 48.3%, respectively, in the 239 patients without a rupture. However, when these patients were compared exclusively with the 8 patients with a corresponding AJCC/UICC 6th ed. TNM stage IIIB disease without a rupture (50 and 0%, respectively), no significant difference was found in the overall survival rates between the groups. CONCLUSION: The surgical outcomes of stage matched patients with and without a ruptured HCC were similar.
