Trabecular Characteristics of Hypertrophic Cardiomyopathy Based on Cardiac Magnetic Resonance Fractal Analysis:A Preliminary Study
10.3969/j.issn.1005-5185.2024.01.010
- VernacularTitle:心脏磁共振分形分析评估肥厚型心肌病心肌小梁特征的初步研究
- Author:
Xin ZHANG
1
;
Jingjing ZHOU
;
Jinyang WEN
;
Tian ZHENG
;
Qimin FANG
;
Xuan XIAO
;
Lianggeng GONG
Author Information
1. 南昌大学第二附属医院影像中心,江西 南昌 330006
- Keywords:
Cardiomyopathy,hypertrophic;
Myocardium;
Magnetic resonance imaging;
Image processing,computer-assisted;
Fractal analysis;
Fractal dimension
- From:
Chinese Journal of Medical Imaging
2024;32(1):56-61
- CountryChina
- Language:Chinese
-
Abstract:
Purpose To evaluate the feasibility of cardiac magnetic resonance fractal analysis in evaluating left ventricular trabecular complexity in hypertrophic cardiomyopathy(HCM),and to study the degree of left ventricular trabecular complexity in HCM and the relationship between excessive trabecular complexity and cardiac function.Materials and Methods From August 2020 to December 2022,a total of 80 patients with HCM from the Second Affiliated Hospital of Nanchang University were retrospectively analyzed.Additionally,80 healthy volunteers were recruited as the control group.Left ventricular functional parameters and fractal dimension(FD)of left ventricular trabecular myocardium were measured.The differences of mean global FD,max basal FD and max apical FD were compared between the HCM group and the control group,the correlation between FDs and cardiac function parameters was evaluated.The diagnostic efficiency of mean global FD,max apical FD and max basal FD was analyzed via receiver operating characteristic curve.Results The mean global FD of HCM group was significantly higher than that of normal group,and the difference was statistically significant(1.303±0.047 vs.1.229±0.026;t=-12.387,P<0.001).Mean global FD showed the best performance in differentiating HCM from normal control group.The optimal cut-off value for the diagnosis of HCM was 1.251,with the area under curve of 0.933(95%CI 0.896-0.969).Mean global FD was positively correlated with maximum wall thickness and left ventricular mass index(r=0.686,0.687,P<0.001),and max apical FD was positively correlated with left ventricular ejection fraction(r=0.520,P<0.001).Conclusion The FD obtained by cardiac magnetic resonance fractal analysis technique is reproducible and has definite value in the diagnosis of HCM,with association with the structure and function of left heart.
