Research Progress of Gd-EOB-DTPA Enhanced MRI in Evaluating Liver Function in Liver Cirrhosis
10.3969/j.issn.1005-5185.2023.12.017
- VernacularTitle:钆塞酸二钠增强MRI评估肝硬化患者肝功能的研究进展
- Author:
Yan ZHANG
1
;
Han FENG
;
Mengchen SONG
;
Guohong CAO
Author Information
1. 树兰(杭州)医院,浙江 杭州 310000
- Keywords:
Liver cirrhosis;
Magnetic resonance imaging;
Contrast media;
Gd-EOB-DTPA;
Liver function;
Review
- From:
Chinese Journal of Medical Imaging
2023;31(12):1328-1331
- CountryChina
- Language:Chinese
-
Abstract:
Liver function can reflect the severity of cirrhosis,and has important clinical value for disease monitoring,efficacy evaluation and surgical risk prediction.At present,the methods commonly used in clinical evaluation of liver function include blood biochemical examination,drug excretion test,comprehensive scoring system and routine imaging examination.All these methods have their limitations.Gd-EOB-DTPA is a hepatocellular specific contrast agent,which is taken up and excreted by liver cells and can directly reflect liver function.Therefore,it is expected to achieve non-invasive segental quantitative evaluation of liver function through enhanced MRI of Gd-EOB-DTPA,which is the focus of current research.In this paper,the methods of Gd-EOB-DTPA enhanced MRI for liver function assessment were reviewed,and the feasibility of Gd-EOB-DTPA in liver function assessment was discussed.