Quantifying Left Ventricular Myocardial Strain Parameters via CT Feature Tracking:the Application in Hypertrophic Obstructive Cardiomyopathy
10.3969/j.issn.1005-5185.2023.12.006
- VernacularTitle:基于CT特征追踪技术量化左心室心肌应变参数在肥厚型梗阻性心肌病中的应用
- Author:
Zeming HE
1
;
Minwen ZHENG
;
Hongliang ZHAO
;
Ziliang XU
;
Shuangxin LI
;
Zilong REN
;
Taiping HE
Author Information
1. 陕西中医药大学医学技术学院,陕西 咸阳 712046
- Keywords:
Hypertrophic obstructive cardiomyopathy;
Tomography,X-ray computed;
Myocardial strain;
Ventricular function,left
- From:
Chinese Journal of Medical Imaging
2023;31(12):1268-1273
- CountryChina
- Language:Chinese
-
Abstract:
Purpose To investigate the feasibility of CT-based feature tracking technology to quantify left ventricular myocardial strain(MS)and its significance in hypertrophic obstructive cardiomyopathy(HOCM).Materials and Methods A total of 35 HOCM patients who underwent cardiac coronary angiography from March 2019 to December 2021 in the First Affiliated Hospital of the Air Force Military Medical University were retrospectively included,and a total of 60 cases who were negative for cardiac coronary angiography among those who visited the hospital with suspected coronary artery disease were randomly enrolled.Conventional cardiac functional parameters and MS parameters were quantified via post-processing software,and differences of parameters between the groups were analyzed.The diagnostic efficacy of MS parameters for HOCM was further evaluated.Results Compared to the control group,the HOCM group exhibited significant increases in various conventional left ventricular functional parameters,including left ventricular wall thickness,mass,mass index,end-diastolic volume and stroke volume(t=2.119 to 24.861,all P<0.05).However,there were no statistically significant differences in end-systolic volume and cardiac output between the two groups(P>0.05).The global longitudinal and radial strain values of HOCM group were significantly lower than those of control group(t=12.857,-6.427,P<0.01),while the endocardial global circumferential strain of HOCM group was significantly higher than that of control group(t=-2.369,P<0.05).Among MS parameters,global longitudinal strain exhibited the best diagnostic efficacy for HOCM,with an area under the curve of 0.997.A cutoff value of≤20.78%for global longitudinal strain showed that the sensitivity and specificity was 100%and 95%,respectively.Conclusion The MS parameters quantified by the CT-based feature tracking technique are superior to left ventricular ejection fraction in quantifying left ventricular function,with the highest sensitivity and specificity for early myocardial function impairment of longitudinal strain.In addition,the technique has good repeatability and is expected to become a new indicator for the assessment of myocardial function in HOCM.
