B1 corrected T1 mapping for distinguishing pathological types and differentiation degrees of lung cancers
10.13929/j.issn.1003-3289.2024.02.016
- VernacularTitle:B1场校正T1 mapping用于鉴别肺癌病理分型及分化程度
- Author:
Zhenzhen LI
1
;
Gaofeng XU
;
Yigang FU
;
Yong XIAO
;
Mingming ZHU
;
Xiao ZHOU
;
Xun SHI
;
Jianqin JIANG
Author Information
1. 南通大学第六附属医院盐城市第三人民医院核医学科,江苏盐城 224000
- Keywords:
lung neoplasms;
pathology;
magnetic resonance imaging;
T1 mapping;
prospective studies
- From:
Chinese Journal of Medical Imaging Technology
2024;40(2):231-234
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the value of B1 corrected T1 mapping for distinguishing pathological types and differentiation degrees of lung cancers.Methods A total of 74 lesions in 65 patients with lung cancers were prospectively enrolled,including 49 poorly differentiated lesions and 25 moderately or well differentiated ones,i.e.42 adenocarcinomas,14 squamous cell carcinomas and 18 small cell lung cancers(all poorly differentiated).B1 corrected T1 mapping was performed,ROI(ROI1 and ROI2)were delineated using 2 methods,and T1 values of different pathological types and differentiation degrees lung cancers were compared.The receiver operating characteristic(ROC)curves were drawn,and the areas under the curve(AUC)were calculated.Results Significant differences of T1 values were found among different pathological types of lung cancer(all P＜0.05),as well as between small cell lung cancer and the rest 2 types of lung cancer(both P＜0.05).There were significant differences of T1 values between poorly differentiated and moderately well differentiated lung cancer(squamous cell carcinoma+adenocarcinoma)(both P＜0.05).Taken ROI1 T1 value=1 524.21 ms as the cut-off value,the AUC of T1 value for distinguishing poorly differentiated and moderately well differentiated lung cancer(squamous cell carcinoma+adenocarcinoma)was 0.698,with sensitivity of 64.50％and specificity of 76.00％.Taken ROI2 T1 value=1 630.68 ms as the cut-off value,the AUC of T1 value was 0.676,with sensitivity of 54.80％and specificity of 80.00％.Conclusion B1 corrected T1 mapping was helpful for distinguishing pathological types and differentiation degrees of lung cancers.
