18 F-FDG PET/MRI manifestations of gray matter heterotopia related to epilepsy
10.13929/j.issn.1003-3289.2024.02.010
- VernacularTitle:脑灰质异位相关癫痫18F-FDG PET/MRI表现
- Author:
Yingxin LI
1
;
Xueying LING
;
Yongjin TANG
;
Yong CHENG
;
Hao XU
Author Information
1. 暨南大学附属第一医院核医学科,广东广州 510630
- Keywords:
nervous system malformations;
gray matter;
epilepsy;
positron-emission tomography;
magnetic resonance imaging
- From:
Chinese Journal of Medical Imaging Technology
2024;40(2):203-207
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe18F-FDG PET/MRI manifestations of gray matter heterotopia(GMH)related epilepsy.Methods Data of 27 patients with GMH and epilepsy diagnosed with MRI were retrospectively analyzed.Brain 18 F-FDG PET/MRI manifestations and complicated brain malformations were observed,and the classification of GMH were performed.Results Among 27 cases,periventricular GMH,focal subcortical GMH,subcortical lamellar(band)GMH and mixed GMH were detected each in 15,2,2 and 8 cases,respectively.Compared with cerebral white matter around the lesion or in the contralateral mirror area of the lesion,glucose hypermetabolism and glucose hypometabolism were found in 22 and 3 cases,respectively,while glucose metabolism was normal in 2 cases.Compared with gray matter in precentral gyrus,glucose hypermetabolism and glucose hypometabolism were observed in 8 and 16 cases,respectively,while glucose metabolism was normal in 3 cases.Six cases complicated with cerebral fissure deformity,6 cases with bilateral cerebellar hemispheric volume reduction,1 case with absence of pellucid septum and lower fornix,1 case with dysplasia of corpus callosum and 1 case with polymicrogyria.Conclusion 18 F-FDG PET/MRI manifestations of GMH related epilepsy had certain characteristics,which were helpful for clinical diagnosis.