MRI observation on abnormal brain activity in patients with migraine without aura
10.13929/j.issn.1003-3289.2024.01.022
- VernacularTitle:MRI观察无先兆偏头痛患者大脑活动异常
- Author:
Chunyang XU
1
,
2
;
Songhua ZHAN
;
Wenli TAN
;
Lei ZHAO
;
Yuying ZHANG
;
Yingnan KONG
;
Yuchan YANG
Author Information
1. 上海中医药大学附属曙光医院放射科,上海 201203
2. 上海中医药大学附属龙华医院放射科,上海 200032
- Keywords:
migraine without aura;
regional homogeneity;
magnetic resonance imaging
- From:
Chinese Journal of Medical Imaging Technology
2024;40(1):112-115
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the abnormal brain activity in patients with migraine without aura(MwoA)with MRI.Methods Fifty MwoA patients(MwoA group)and 46 healthy volunteers(control group)were prospectively enrolled.Functional MRI(fMRI)was performed to observe the dynamic regional homogeneity(dReHo)of brain regions,then brain regions with differences of dReHo value between groups were extracted,and correlations with clinical scales were analyzed.Results Compared with control group,dReHo values of surrounding cortex of bilateral calcarine fissure and right middle occipital gyrus increased,of right middle temporal gyrus,right middle frontal gyrus and left cuneus decreased in MwoA group(GRF correction,voxel level all P＜0.005,cluster level all P＜0.05).The weight analysis showed that brain regions with top 3 absolute weight values were surrounding cortex of right calcarine fissure,left cuneus and right middle occipital gyrus.dReHo value of surrounding cortex of left calcarine fissure in MwoA patients was negative correlated with self-rating depression scale(SDS)(r=-0.28,P=0.04).Conclusion Abnormalities in the upward transmission pathway of visual information existed in MwoA patient,especially in surrounding cortex of right calcarine fissure,left cuneus and right middle occipital gyrus.
