Ultrasound-guided percutaneous ethanol injection combined with microwave ablation for treatment of thyroid benign partially cystic masses
10.13929/j.issn.1003-3289.2024.01.006
- VernacularTitle:超声引导下经皮注射无水乙醇联合微波消融治疗甲状腺良性囊实性肿物
- Author:
Yujiang LIU
1
;
Ruifang XU
;
Linxue QIAN
;
Junfeng ZHAO
Author Information
1. 首都医科大学附属北京友谊医院超声科,北京 100050
- Keywords:
thyroid nodule;
ethanol;
ablation techniques;
ultrasonography;
prospective studies
- From:
Chinese Journal of Medical Imaging Technology
2024;40(1):32-36
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the value of ultrasound-guided percutaneous ethanol injection(PEI)combined with microwave ablation(MWA)for treating thyroid benign partially cystic masses.Methods A total of 100 patients with single benign partially cystic mass who would undergo ultrasound-guided ablation treatment were prospectively enrolled.The patients were randomly assigned into PEI group(received PEI combined with MWA sequential ablation)or control group(received simple MWA),each n=50.Data before and after treatments were compared within groups,the therapeutic efficacy were compared between groups after treatments,and the value of sequential ablation was analyzed.Results Ultrasound-guided ablation was successfully performed for all 100 masses.During follow-up,5 cases in PEI group and 3 cases in control group were lost.The operation time of MWA,total MWA energy and patients'pain level during treatments in PEI group were all lower than those in control group(all P＜0.05).Significant difference of thyroid mass volumes were found before and 3,6 and 12 months after treatments in both groups(all P＜0.05).The volume reduction rate(VRR)in PEI group before and 1,3,6 and 12 months after treatments were all higher than that in control group(all P＜0.05).The success rate was 95.56％(43/45)in PEI group and 89.36％(42/47)in control group 12 months after treatments,respectively,without significant difference(P=0.451).There were significant differences of neck aesthetics scores and symptom scores before and 3,6 and 12 months after treatments in both groups(all P＜0.05).The incidence of complications in PEI group was 6.67％(3/45),while in control group was 14.89％(7/47),the former was lower than the latter(P＜0.05).Conclusion Ultrasound-guided PEI combined with MWA sequential ablation had better effect for treating thyroid benign partially cystic masses than single MWA.
