Dynamic contrast enhanced MRI combined with intravoxel incoherent motion for preoperative evaluation on pathological type of rectal cancer
10.13929/j.issn.1003-3289.2023.12.021
- VernacularTitle:动态对比增强MRI联合体素内不相干运动术前评估直肠癌病理分型
- Author:
Yaxin CHAI
1
;
Yongchao NIU
Author Information
1. 新乡市中心医院新乡医学院第四临床学院磁共振室,河南新乡 453500
- Keywords:
rectal neoplasms;
adenocarcinoma;
intravoxel incoherent motion;
magnetic resonance imaging
- From:
Chinese Journal of Medical Imaging Technology
2023;39(12):1833-1837
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the value of dynamic contrast enhanced MRI(DCE-MRI)combined with intravoxel incoherent motion(IVIM)for preoperative evaluation on pathological type of rectal cancer.Methods Totally 81 patients with rectal adenocarcinoma were enrolled and divided into mucinous adenocarcinoma group(n=36)or non mucinous adenocarcinoma group(n=45)based on postoperative pathological results.Parameters of DCE-MRI and IVIM,including rate constant(Kep),volume transfer constant(Ktrans),extravascular extracellular volume fraction(Ve),true diffusion coefficient(D),pseudo diffusion coefficient(D*)and perfusion fraction(f)were compared between groups.Logistic regression analysis was performed,the efficacy of the above parameters for evaluation on pathological type of rectal cancer were explored.Results Kep,Ktrans,D*and f of mucinous adenocarcinoma group were all smaller than those of non mucinous adenocarcinoma group(all P＜0.05).Kep and f were both impact factors of pathological type of rectal cancer(both P＜0.05).The area under the curve(AUC)of Kep,f and Kep+f for preoperative evaluation on pathological type of rectal cancer was 0.774,0.880 and 0.906,respectively,with sensitivity of 69.44％,77.78％and 86.11％,specificity of 82.22％,91.11％and 91.11％,respectively.AUC of Kep was lower than that of Kep+f(P＜0.05).Conclusion DCE-MRI combined with IVIM could effectively evaluate the pathological type of rectal cancer preoperation.
