Quantitative CT for predicting efficacy of medical thoracoscopic giant emphysematous bullae volume reduction
10.13929/j.issn.1003-3289.2023.12.017
- VernacularTitle:定量CT预测内科胸腔镜下巨型肺大疱减容术疗效
- Author:
Tingting LIANG
1
,
2
;
Yaohua YU
;
Zhenhua LI
;
Guoyan LI
;
Xinna ZHANG
;
Hua ZHANG
Author Information
1. 新乡医学院研究生院,河南 新乡 453000
2. 郑州大学附属郑州中心医院呼吸与危重症医学科,河南 郑州 450000
- Keywords:
pulmonary disease,chronic obstructive;
endoscopic lung volume reduction;
tomography,X-ray computed
- From:
Chinese Journal of Medical Imaging Technology
2023;39(12):1819-1822
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the value of quantitative CT(QCT)for predicting the efficacy of medical thoracoscopic giant emphysematous bullae(GEB)volume reduction.Methods Data of chest QCT and pulmonary function tests before and 6 months after medical thoracoscopic volume reduction in 26 chronic obstructive pulmonary disease(COPD)patients complicated with GEB who underwent medical thoracoscopic GEB volume reduction were retrospectively analyzed.According to the improvement rate of lung function(forced expiratory volume in one second[FEV1])6 months after treatment compared with that before treatment,the patients were divided into significant improvement group(FEV1 improvement rate≥15％,n=20)and non-significant improvement group(FEV1 improvement rate＜15％,n=6).QCT parameters before treatment were compared between groups,and the correlations of QCT parameters being significantly different between groups with FEV1 improvement 6 months after treatment were analyzed.Then receiver operating characteristic(ROC)curves were drawn to evaluate the efficacy of the above parameters for predicting the curative effect of medical thoracoscopic volume reduction of GEB.Results Significant differences of preoperative target lung lobe volume,total lung volume and bullae volume were found between groups(all P＜0.05).Preoperative target lung lobe volume,total lung volume,target lobar bullae volume and total lung bullae volume were positively correlated with FEV1 improvement(r/rs=0.600,0.470,0.699,0.523,all P＜0.05),with the area under the curve(AUC)for predicting FEV1 improvement of 0.817,0.817,0.892 and 0.833(all P＜0.05),respectively.Conclusion QCT could effectively predict the efficacy of medical thoracoscopic GEB volume reduction.
