Fluorescent probes and imaging techniques for deep-tissue optical imaging:a review
10.3969/j.issn.1005-202X.2024.02.007
- VernacularTitle:用于深层组织光学成像的荧光探针与成像技术
- Author:
Yuxiang GAO
1
;
Le GUO
;
Hui LI
;
Xueliang ZHANG
;
Nuernisha ALIFU
Author Information
1. 新疆医科大学医学工程技术学院,新疆乌鲁木齐 830011
- Keywords:
optical imaging;
near-infrared Ⅱ region;
bioluminescence;
chemiluminescence;
adaptive optics;
review
- From:
Chinese Journal of Medical Physics
2024;41(2):169-174
- CountryChina
- Language:Chinese
-
Abstract:
The research advancements in probes for deep-tissue imaging and adaptive optical imaging technologies are summarized,aiming to offer a new perspective for life science and interdisciplinary research.The review firstly gives an introduction on the probes emitting in the near-infrared-Ⅱ region,including fluorescence,bioluminescence,chemiluminescence,and persistent luminescence,and then elaborates direct sensing methods for rapid measurement and correction of wavefront distortions,as well as indirect sensing methods for correcting complex optical aberrations.The continuous updating of the above techniques and methods has enabled optical imaging to successfully penetrate deeper tissues with a remarkable reduction of background noise for higher image quality.
