Coil design and simulation analysis of magnetic induction hyperthermia in rats
10.3969/j.issn.1005-202X.2024.01.015
- VernacularTitle:大鼠磁感应热疗的线圈设计与仿真分析
- Author:
Siwei GUO
1
;
Mai LU
Author Information
1. 兰州交通大学光电技术与智能控制教育部重点实验室,甘肃兰州 730000
- Keywords:
magnetic induction hyperthermia;
coil;
coupling field;
rat model
- From:
Chinese Journal of Medical Physics
2024;41(1):101-108
- CountryChina
- Language:Chinese
-
Abstract:
A Helmholtz coil is selected to generate the alternating magnetic field,and the relevant model is established with a rat brain tumor as the research object.Based on the Pennes bioheat transfer equation,the electromagnetic field distribution and temperature field distribution are calculated in COMSOL simulation software,and the factors affecting the outcome of magnetic induction hyperthermia are analyzed.The results show that both magnetic field distribution and temperature field distribution meet the requirements for magnetic induction hyperthermia.The magnetic field distribution in the tumor treatment area is uniform,and the central magnetic induction strength is 12.847 mT.The temperature rise in the tumor area is significant,and the temperature at the tumor center is 46℃or above,basically reaching the treatment temperature.The therapeutic efficacy of magnetic induction hyperthermia is affected by the number of turns,current,radius and spacing,magnetic field frequency and other parameters.The study provides reference for the clinical application of magnetic induction hyperthermia and the coil design.
