Study on clinical efficacy and safety of Yiqi Kaimi decoction combined with acupoint catgut embedding in the treatment of chronic constipation of qi deficiency type
10.12173/j.issn.1008-049X.202311102
- VernacularTitle:益气开秘汤联合穴位埋线治疗气虚型慢性便秘的临床疗效和安全性研究
- Author:
Wei ZHANG
1
;
Dong-Mei WEI
;
Chun YU
Author Information
1. 陕西省中医医院脾胃病一科(西安 710002)
- Keywords:
Yiqi Kaimi decoction;
Acupoint catgut embedding;
Qi deficiency type chronic constipation;
Clinical efficacy;
Security
- From:
China Pharmacist
2023;26(12):465-471
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical efficacy and safety of Yiqi Kaimi decoction combined with acupoint embedding in patients with chronic constipation with qi deficiency.Methods Patients with chronic constipation with qi deficiency who were diagnosed and treated in Shaanxi Provincial Hospital of Traditional Chinese Medicine from January 2022 to June 2023 were enrolled and divided into control group and test group.The control group was given conventional treatment and acupoint embedding,and the test group was treated with Yiqi Kaimi decoction on the basis of the control group.The differences in TCM syndrome scores,defecation traits,quality of life,serum nitric oxide(NO)and substance P(SP)levels between the two groups before and after treatment were observed and compared.The occurrence of adverse reactions during the treatment of patients was observed,and safety evaluation was carried out.Results A total of 80 patients with chronic constipation with qi deficiency were included in the study,including 40 patients in the test group and 40 cases in the control group.After treatment,the TCM syndrome scores(defecation time,defecation interval,difficulty in defecation,cold pain in the abdomen and warmth in the limbs)of the test group were lower than those of the control group(P<0.05).The serum NO in the test group was lower than that in the control group,while the serum SP was higher than that in the control group(P<0.05).During the treatment,there were no obvious abnormalities in liver and kidney function,vomiting,diarrhea and other gastrointestinal discomfort symptoms in the two groups,and there was no abnormal phenomenon at the thread embedding site.Conclusion Yiqi Kaimi decoction combined with acupoint embedding has a significant effect in the treatment of qi deficiency chronic constipation,and can improve the TCM syndrome score,defecation traits and quality of life of patients by regulating serum NO and SP.
