Mechanism of Ki-67 in lung cancer and related progress in research on radiomics

VernacularTitle:肺癌中Ki-67的作用机制及影像组学的相关研究进展
Author: Yuze WEI ¹ ; Zaiming LU ; Ying REN
Author Information

1. 中国医科大学附属盛京医院放射科,沈阳 110004
Keywords: lung cancer; radiomics; Ki-67; texture analysis
From: Journal of China Medical University 2024;53(3):271-275
CountryChina
Language:Chinese
Abstract: Radiomics is a new diagnostic and treatment technology,which can be employed to extract high-throughput radiomics features from CT,MR,and PET images and screen features closely related to diagnostic and treatment purposes,so as to accurately predict tumor or disease classification,prognosis,or genomic changes.Ki-67 is a type of nuclear protein,which is present only in nuclei of proliferative and dividing cells but not in those of quiescent phase cells;hence,it can be used as a predictor of cell proliferation and has been proven to be closely related to prognosis of lung cancer.This article reviews the mechanism and progress in radiomics research related to Ki-67 in lung cancer.