Changes in the isolation and drug resistance rate of Escherichia coli in a hospital over the past 10 years
10.12007/j.issn.0258-4646.2024.03.014
- VernacularTitle:某医院近10年大肠埃希菌分离率和耐药率的变迁情况
- Author:
Lijie GUO
1
;
Fushun LI
;
Jingjing CHEN
;
Qihui WANG
;
Yunzhuo CHU
Author Information
1. 中国医科大学附属第一医院检验科,沈阳 110001
- Keywords:
bacterial drug resistance monitoring;
drug sensitivity test;
Escherichia coli
- From:
Journal of China Medical University
2024;53(3):266-270
- CountryChina
- Language:Chinese
-
Abstract:
Objective To summarize the isolation and drug resistance rate of Escherichia coliin The First Hospital of China Medical University over the past 10 years,in order to provide evidence for the efficacies of clinical anti-infection treatments.Methods The data was collected from Escherichia coli isolated from patients treated at The First Hospital of China Medical University between 2013 and 2022.VITEK 2 and VITEK MS were used for bacterial identification,VITEK2 and KB method were used for drug sensi-tivity testing,and WHONET 5.6 software was used for analysis.Results From 2013 to 2022,6 845 strains were isolated,including 80.5%from inpatients and 19.5%from emergency and outpatients.The specimens were most commonly found in the urine(57.8%),blood(15.0%),secretions(9.2%),and drainage fluid(8.1%).The isolation rate of extended-spectrumβ-lactamase(ESBL)producing Escherichia coli was 57.2%(54.3%to 61.5%).The drug resistance rate of Escherichia coli to carbapenems was low,at only 1.2%(0.2%to 2.6%).Conclusion Escherichia coli remains an important pathogen in clinical infections,with varying degrees of resist-ance to multiple antibiotics,and the resistance rate is increasing.Clinical physicians should pay sufficient attention to this issue.
