Value of imaging features and laboratory indicators in predicting microvascular invasion of hepatocellular carcinoma
10.12007/j.issn.0258-4646.2024.01.012
- VernacularTitle:肝细胞癌影像特征结合实验室指标在微血管侵犯中的预测价值
- Author:
Cong DAI
1
;
Wenyuan LIU
;
Xuantong LIU
;
Mingyu ZOU
Author Information
1. 北部战区总医院放射诊断科,沈阳 110016
- Keywords:
hepatocellular carcinoma;
microvascular invasion;
CT;
magnetic resonance imaging;
alpha-fetoprotein
- From:
Journal of China Medical University
2024;53(1):75-79
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the prediction of microvascular invasion(MVI)and its grading in patients with hepatocellular carcinoma(HCC)by computed tomography(CT)and magnetic resonance imaging(MRI)features combined with laboratory indices.Methods Using plain and enhanced CT and MRI scan to examine the participants preoperatively,the features of tumor length diam-eter,shape,number,margin and tumor capsule,whether multiple nodules are fused,whether external convex nodules are visible locally,whether blood supply vessels are visible inside or degeneration or necrosis exists,and whether low density or signal exists around the tumor that are extracted from the examination results,combined with clinical indicators,such as age,preoperative alpha-fetoprotein(AFP)level,and presence of hepatitis B surface and e antigens to analyze the occurrence of MVI in patients with HCC.Results Patients with HCC and MVI were more likely to have elevated AFP;the larger the tumor length and diameter,the higher the incidence of MVI.CT and MRI showed that the features of blurred tumor edges and incomplete local capsule were independent risk factors for MVI of HCC.All the extracted image features and clinical indicators had no predictive value for MVI grading.Conclusion A few imaging features and clin-ical indicators of HCC have definite predictive value for the occurrence of MVI.
