Amplitude of Low-frequency Sub-band in Resting State Functional Magnetic Resonance Imaging after Anterior Cruciate Ligament Reconstruction
10.3969/j.issn.1000-6710.2023.11.002
- VernacularTitle:前交叉韧带重建术后重返运动的静息态功能磁共振低频振幅亚频段研究
- Author:
Hongyun SONG
1
;
Hangjun LOU
;
Yuanqing SHEN
;
Sunan ZHU
;
Fangyao XIE
;
Xiaojing YU
;
Xuesong DAI
Author Information
1. 浙江大学医学院附属第二医院,浙江大学骨科研究所,浙江省运动系统疾病研究与精准诊治重点实验室,浙江省运动系统疾病临床诊疗中心(杭州 310009)
- Keywords:
anterior cruciate ligament reconstruction;
functional magnetic resonance;
amplitude of low-frequency;
return to sports
- From:Chinese Journal of Sports Medicine
2023;42(11):860-866
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the difference of brain function remodeling in patients with differ-ent motor ability and record the brain function index of patients returning to exercise 2 years after an-terior cruciate ligament reconstruction(ACLR).Methods Patients undergoing ACLR in year 2017 and 2018(2 years after ACLR)were selected and randomly divided into a return-to-exercise(CP,n=7)group,a non-return-to-exercise(NP,n=7)group.Moreover,8 healthy counterparts of the CP group were chosen into a healthy control(HC)group.Resting state functional magnetic resonance imaging(rs-fMRI)was used to obtain the blood oxygen level dependent signals,and the amplitude of low-frequen-cy fluctuation(ALFF)was computed across the typical band(0.01～0.08 Hz),sub-band Slow-4(0.027～0.073 Hz)and Slow-5(0.01～0.027 Hz).Meanwhile,brain maps were obtained and two-sample t-tests were performed among different groups(P<0.005).Results In the typical frequency band,the average ALFF value was higher in the CP and HC groups than the NP group for the Cerebelum_Crus1,but lower in the CP group than the NP group for the Occipital_Mid,higher in the CP group than the HC group for the Putamen and higher in the NP group than the HC group for the Frontal_Mid_Orb.More-over,in the Slow-4 band,the ALEF level was lower in the CP group than the NP group for the Oc-cipital_Mid,higher in the CP group than the HC group for the Putamen,and higher in the NP group than the HC group for the Frontal_Mid_Orb and cerebellum_Crus2.However,in the Slow-5 band,the ALEF values were higher in the CP group than the NP group for the Occipital_Inf and Precen-tral,but lower for the caudate.In the same band,those values were higher in the CP group than in the HC group for the Cerebellum_Crus1,but lower in the NP group than the HC group for the Cere-bellum_Crus1 and Supp_Motor_Area,and higher in the NP group than the HC group for the Fron-tal_Mid_Orb.Conclusion The patients returning to exercise after ACLR have higher cerebellar remodel-ing and lower visual compensation than those not,and display higher basal ganglia and cerebellar nerve remodeling than healthy controls,suggesting that functional compensation occurs in the former pa-tients.Moreover,Slow-4,Slow-5 and other sub-bands can complement the classical frequency bands and are worthy of further study.
