Mediating effect of rumination on anxiety, depression and quality of life in adult patients with epilepsy
10.3760/cma.j.cn371468-20230227-00099
- VernacularTitle:反刍思维在成年癫痫患者焦虑抑郁与生活质量间的中介效应
- Author:
Baojun QIAO
1
;
Ranran XU
;
Liang ZHANG
;
Hui YAN
;
Huanxia LI
;
Yanlei HAO
Author Information
1. 济宁医学院附属医院神经内科，济宁 272100
- Keywords:
Rumination;
Epilepsy;
Anxiety;
Depression;
Quality of life;
Mediating effect
- From:
Chinese Journal of Behavioral Medicine and Brain Science
2023;32(11):1005-1010
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the mediating effect between anxiety, depression and quality of life in adult patients with epilepsy.Methods:A total of 118 adult patients with epilepsy from Affiliated Hospital of Jining Medical University were investigated with the ruminative responses scale (RRS), neurological disorders depression inventory for epilepsy (NDDI-E), generalized anxiety disorder (GAD-7), quality of life scale for adult epilepsy patients (QOLIE-31 Chinese Version) and the self-made general situation questionnaire. Statistical analysis was performed by SPSS 20.0 software.Pearson correlation analysis was employed to assess the relationships between rumination, quality of life, anxiety, and depression scores. Hierarchical regression analysis was employed to examine the mediating effect.Results:Among the 118 participants, 5 (4.24%), 58 (49.15%), and 55 (46.61%) patients exhibited high (RRS=66-88), middle (RRS=44-65), and low (RRS=22-43) level of rumination, respectively. Pearson correlation analysis revealed significantly negative correlations between the scores of rumination and its dimensions and quality of life in patients with epilepsy ( r=-0.411--0.318, all P<0.05). Additionally, there were significantly positive correlations between the scores of rumination and its dimensions and anxiety scores ( r=0.524-0.676, all P<0.05) and depression scores ( r=0.566-0.767, all P<0.05). Hierarchical regression analysis demonstrated that rumination played partially mediating role in the relationship between anxiety and quality of life, as well as the relationship between depression and quality of life, with mediation effect values of -0.201 and -0.215, respectively. Conclusion:Anxiety and depression can affect the quality of life of adult patients with epilepsy through rumination.
