Comparison of demographic and clinical characteristics of bipolar Ⅰ disorder and bipolar Ⅱ disorder
10.3969/j.issn.1000-6729.2024.01.005
- VernacularTitle:双相Ⅰ型障碍和双相Ⅱ型患者人口学和临床特征的比较
- Author:
Li ZHOU
1
;
Yiling XIE
;
Tingting ZHANG
;
Yueqin HUANG
;
Liang ZHOU
;
Yan LIU
;
Bo LIU
;
Jie ZHANG
;
Yuandong GONG
;
Zhongcai LI
;
Bi LI
;
Zhipeng LI
;
Qingyuan ZENG
;
Zonglin SHEN
;
Wenming CHEN
;
Zhaorui LIU
;
Jin LU
Author Information
1. 云南省精神病医院,昆明 650224
- Keywords:
bipolar Ⅰ disorder;
bipolar Ⅱ disorder;
clinical characteristics;
physiological indicators;
treat-ment patterns
- From:
Chinese Mental Health Journal
2024;38(1):33-41
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To compare demographic characteristics,clinical characteristics,therapeutic characteris-tics and physiological indicators of patients with bipolar Ⅰ disorder and bipolar Ⅱ disorder.Methods:A total of 381 patients with bipolar disorder(BD)diagnosed by the Diagnostic and Statistical Manual of Mental Disorders 5 th Edi-tion(DSM-5)were selected,including 302 patients with BD-Ⅰ(79.27％),74 patients with BD-Ⅱ(19.42％)and 5 patients with other specific and related disorders(1.31％).Demographic and clinical characteristics were collected with self-designed clinical information questionnaire.Multivariate logistic regression and multivariate linear regres-sion analysis were used for analysis.Results:Compared with patients with BD-Ⅱ,patients with BD-Ⅰ had more risk to have psychotic features(OR=5.75,95％CI:2.82-11.76),longer disease duration,and more repeated transcra-nial magnetic therapy(OR=3.09,95％CI:1.02-9.35),higher uric acid,total cholesterol and high-density lipo-protein.BD-Ⅰ in Han nationality was more common(OR=11.50,95％CI:1.76-75.30),and had lower education level(OR=10.22,95％CI:1.16-89.77),and less family history of psychosis(OR=2.34,95％CI:1.01-5.42).Conclusion:There are significant differences between BD-Ⅰ and BD-Ⅱ in demographic and clinical charac-teristics,treatment status,and physiological indicators,which could provide clues for exploring the pathogenesis of bipolar disorder.
