Progression,Imaging Characteristics of Left Ventricular Remodeling and the Clinical Value on Decision-making of Intervention in Patients With Aortic Stenosis
10.3969/j.issn.1000-3614.2024.03.014
- VernacularTitle:主动脉瓣狭窄患者左心室重构的过程、影像学特点与治疗决策
- Author:
Qiaofan CHEN
1
;
Yunqing YE
;
Erli ZHANG
;
Haiyan XU
;
Yongjian WU
Author Information
1. 中国医学科学院 北京协和医学院 国家心血管病中心 阜外医院 心内科,北京 100037
- Keywords:
aortic stenosis;
left ventricular remodeling;
myocardial hypertrophy;
myocardial fibrosis;
aortic valve replacement
- From:
Chinese Circulation Journal
2024;39(3):294-300
- CountryChina
- Language:Chinese
-
Abstract:
Aortic stenosis is a valve disease characterized by dynamic and continuous changes in structure and function of left ventricle.Left ventricular remodeling,which embodies pathological changes in myocardial cellular and ventricular geometry,is an important prognostic factor of patients with aortic stenosis.Aortic valve replacement is the only effective treatment for severe aortic stenosis.Current guideline recommendations for interventions are based on symptoms and left ventricular ejection fraction.With the improvements of modern imaging technology,different patterns of remodeling,including hypertrophy and fibrosis,could be identified now.Studies also explored the close association between left ventricular remodeling and function in the setting of aortic stenosis.In this review,we aim to elucidate the characteristic imaging features and potential mechanisms of left ventricular remodeling,and further,we highlight the clinical value of specific imaging features and clinical application of modern imaging methods in the evaluation,risk stratification,and intervention decision-making for patients with aortic stenosis.
