Brugada-like Electrocardiographic Changes Induced by Propafenone:a Case Report
10.3969/j.issn.1000-3614.2024.02.013
- VernacularTitle:普罗帕酮诱发Brugada样心电图改变一例
- Author:
Yu ZHANG
1
;
Xianyi XIN
;
Yan ZHOU
Author Information
1. 吉林大学第一医院 小儿心血管科,长春 130021
- Keywords:
Brugada syndrome;
propafenone;
atrial flutter
- From:
Chinese Circulation Journal
2024;39(2):194-198
- CountryChina
- Language:Chinese
-
Abstract:
Brugada syndrome presents mainly in adulthood,and sudden death occurs mainly at rest or during sleep.It is uncommon in childhood,especially with atrial flutter as the first manifestation.In this article,we report a case of a 13-year-old child with atrial flutter as the first manifestation,without underlying cardiac disease,who developed Brugada-like electrocardiographic changes during the treatment of propafenone,and genetic testing revealed the suspected mutant genes SCN5A(c.2834A＞G[p.D945G]).Present case and related literature review might improve the awareness of clinicians on the inducing factors of Brugada syndrome and related a variety of cardiac arrhythmias,the importance of electrocardiogram monitoring during the application of antiarrhythmic drugs,and provide guidance and close follow-up strategies to this high-risk group,so as to avoid the occurrence of adverse events in these patients.
