Research Progress in Obesity Related Heart Failure
10.3969/j.issn.1000-3614.2024.01.012
- VernacularTitle:肥胖相关性心力衰竭的研究进展
- Author:
Qier AN
1
;
Yanyan CHEN
Author Information
1. 中国医学科学院 北京协和医学院 国家心血管病中心 阜外医院 内分泌中心,北京 100037
- Keywords:
heart failure;
obesity;
heart remodeling;
weight loss
- From:
Chinese Circulation Journal
2024;39(1):89-94
- CountryChina
- Language:Chinese
-
Abstract:
The prevalence rate of heart failure is increasing year by year,posing a significant threat to human health,partly due to the rapid growth of overweight and obese populations.Obesity,as an independent risk factor of heart failure,affects hemodynamics,cardiac structure and cardiac function through mechanisms such as adipocyte release of adipokines,insulin resistance and accumulation of epicardial adipose tissue.Although the results of whether weight loss can reduce heart failure incidence are inconsistent,weight loss is associated with benefits such as reduced symptoms and comorbidities,and improved quality of life.Weight loss thus plays an indispensable role in the prevention and management of cardiovascular diseases in obese individuals.Currently,effective weight loss strategies confirmed by evidence-based studies mainly include lifestyle interventions,medication therapy and weight loss surgery.
