Correlation Between Mitral Annular Calcification and Recurrence of Atrial Fibrillation After Radiofrequency Ablation
10.3969/j.issn.1000-3614.2023.12.007
- VernacularTitle:二尖瓣瓣环钙化与心房颤动射频导管消融术后复发的相关性研究
- Author:
Jia XUE
1
;
Bing LI
;
Chenxi JIANG
;
Wei WANG
;
Ribo TANG
;
Deyong LONG
;
Jianzeng DONG
;
Yan YAO
Author Information
1. 首都医科大学附属北京安贞医院 心内科,北京 100029
- Keywords:
atrial fibrillation;
mitral annular calcification;
radiofrequency ablation;
recurrence
- From:
Chinese Circulation Journal
2023;38(12):1274-1278
- CountryChina
- Language:Chinese
-
Abstract:
Objectives:To explore the correlation between mitral annulus calcification(MAC)and recurrence of atrial fibrillation(AF)after radiofrequency ablation. Methods:The study included 785 patients with AF who underwent radiofrequency ablation in Beijing Anzhen Hospital from January 1,2019 to December 31,2020.According to the recurrence of AF after operation,patients were divided into recurrence group and non-recurrence group.Univariate Cox regression model was used to analyze the risk factors associated with AF recurrence,and multivariate Cox regression model was used to evaluate the influence of MAC on AF recurrence. Results:The average follow-up was(16±10)months.190 patients(24.2%)in the recurrence group,595(75.8%)patients in the non-recurrence.Patients in the recurrence group were older,had a higher proportion non-paroxysmal AF,a higher proportion of MAC,moderate/severe mitral regurgitation and larger left atrial diameter(LAD),and higher CHA2DS2-VASc score(all P<0.001).Univariate analysis showed that MAC was a risk factor of AF recurrence after radiofrequency ablation(HR=2.530,95%CI:1.639-3.907,P<0.001).After adjusting for age and sex,MAC remained significantly associated with an increased risk of AF recurrence after radiofrequency ablation(HR=1.52,95%CI:1.14-2.17,P<0.001).After multivariate adjustment for age,sex,non-paroxysmal AF,hypertension,diabetes,LAD,moderate/severe mitral regurgitation,and CHA2DS2-VASc score,MAC remained as an independent risk factor of AF recurrence(HR=1.48,95%CI:1.13-1.95,P=0.001). Conclusions:MAC is significantly associated with an increased risk of AF recurrence after radiofrequency ablation.
