Health Economic Evaluation of Hepatocellular Carcinoma Screening and Optimal Delicacy Management Strategies in China
- VernacularTitle:我国肝癌筛查及肝病精细化管理策略的卫生经济学评价
- Author:
Qing XIE
1
;
Fangzhou WANG
;
Liyue ZHANG
;
Shuli QU
;
Jingya WU
;
Yihan LIAO
;
Chunlin JIN
Author Information
1. 上海交通大学医学院附属瑞金医院 上海 200025
- Keywords:
hepatocellular carcinoma;
liver disease delicacy management;
screening;
cost-effectiveness
- From:
Chinese Health Economics
2024;43(2):16-20
- CountryChina
- Language:Chinese
-
Abstract:
Objective:Based on the cost-effectiveness,it aimed to assess the health benefits amd economic value of screening,di-agnosis,treatment,and optimal delicacy management of liver disease in hepatocellular carcinoma(HCC)patients.Methods:A Deci-sion tree-Markov model was developed to compare the cost-effectiveness of HCC screening and long-term surveillance versus no screening in population at risk from the health care system perspective.Results:It is found that HCC screening was a cost-effective approach compared to no screening(Incremental Cost-Effectiveness Ratio[ICER]:17 790 yuan/QALY).Scenario analyses suggested that initiating HCC screening at the age of 40,as recommended by clinical guidelines,and implementing long-term surveillance based on risk stratification were more cost-effective.Conclusions:For the implementation of HCC screening programs,attention should be paid to improving participation and compliance among the population at risk,incorporating advanced screening methods,improving management efficiency with digital tools,and introducing innovative payment methods to reduce economic burden.