Research progress in the metabolism of branched-chain amino acids and obesity related insulin resistance

VernacularTitle:支链氨基酸代谢和肥胖与胰岛素抵抗相关性的研究进展
Author: Yuxiu WANG ¹ ; Juan ZHENG ; Jiaoyue ZHANG ; Hua LIU ; Lulu CHEN
Author Information

1. 430020 武汉,华中科技大学同济医学院附属协和医院内分泌科
Keywords: Branched-chain amino acids; Obesity; Insulin resistance; Diabetes mellitus
From: Chinese Journal of Diabetes 2024;32(3):215-217
CountryChina
Language:Chinese
Abstract: Obese patients may have abnormal metabolism of branched-chain amino acids(BCAA).Elevated levels of BCAA can lead to insulin resistance(IR)through various mechanisms,which may make it a sensitive indicator for predicting the occurrence of diabetes mellitus.This article reviews the research progress on the correlation between BCAA metabolism,obesity and IR.