Research progress on the pathogenesis of painful diabetic peripheral neuropathy
10.3969/j.issn.1006-6187.2024.02.013
- VernacularTitle:痛性糖尿病周围神经病变发生机制的研究进展
- Author:
Xuanwei ZHANG
1
;
Xinfeng LIU
;
Kaiyu NIE
Author Information
1. 563000 遵义医科大学
- Keywords:
Painful diabetic peripheral neuropathy;
Mechanism;
Dorsal horn of thespinal cord
- From:
Chinese Journal of Diabetes
2024;32(2):149-154
- CountryChina
- Language:Chinese
-
Abstract:
Painful diabetic peripheral neuropathy(PDPN)is a chronic complication of diabetes mellitus.The proportion of patients with PDPN is relatively high in China.At present,the latest guidelines recommend a batch of first-line analgesic drugs for PDPN treatment.Many large-scale randomized trials have confirmed the effectiveness of combination therapy.However,the pathological and physiological mechanisms of PDPN are not fully understood.The clinical treatment effect is still not ideal.This article reviews the research progress on the mechanism of PDPN occurrence.