Association between different obesity indicators and carotid intima-media thickness in patients with type 2 diabetes mellitus
10.3969/j.issn.1006-6187.2023.12.006
- VernacularTitle:2型糖尿病患者不同肥胖指标与颈动脉内膜中层厚度的关系
- Author:
Qian CUI
1
;
Qingqing LOU
;
Zhenzhen SUN
;
Xinhua YE
;
Ping YANG
;
Dan FANG
;
Ping YAO
;
Xiaodan YUAN
Author Information
1. 213000 常州,南京医科大学附属常州第二人民医院内分泌科
- Keywords:
Diabetes mellitus,type 2;
Obesity indicator;
Carotid intima-media thickness
- From:
Chinese Journal of Diabetes
2023;31(12):909-915
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relationship between different obesity indicators and carotid intima-media thickness(CIMT)in patients with type 2 diabetes mellitus(T2DM).Methods A total of 1762 T2DM patients who visited the Endocrinology Department of Changzhou Second People's Hospital Affiliated with Nanjing Medical University and the Integrated Traditional Chinese and Western Medicine Hospital Affiliated with Nanjing University of Traditional Chinese Medicine from January 2019 to February 2022 were enrolled in this study.They were divided into youth group(18～44 years old,n=402),middle aged group(45～59 years old,n=1032),and elderly group(≥60 years old,n=328)according to WHO age classification criteria.The influencing factors for CIMT thickening in T2DM patients were analyzed using binary logistic regression,and the evaluation of the predictive effect of different obesity indicators on CIMT thickening was evaluated by receiver operating characteristic(ROC)curves.Results The subcuta-neous fat area,visceral fat area(VFA),neck circumference(NC),BMI,WC,cardiac metabolic index(CMI),Chinese visceral fat index(CAVI),visceral fat index,triglyceride glucose index,body roundness index,lipid aggregation index,HbA1c,DBP,TC,TG,HDL-C,LDL-C were lower in the middle aged and elderly groups than in youth group(P＜0.05).Binary logistic regression showed that VFA,NC,CMI in young T2DM patients,CAVI in middle aged T2DM patients,and NC in elderly T2DM patients were influ-encing factors for CIMT thickening.ROC curve analysis showed that VFA in young T2DM patients,CAVI in middle aged T2DM patients,and NC in elderly T2DM patients had a better predictive effect on CIMT thickening,with areas under the ROC curve of 0.567,0.574,and 0.573 respectively.Conclusion VFA,CAVI,and NC have a certain predictive effect on CIMT thickening in young,middle aged,and elderly T2DM patients.
