Research progress in evaluation of type 2 diabetic peripheral neuropathy animal model
10.3969/j.issn.1671-7856.2024.01.018
- VernacularTitle:2型糖尿病周围神经病变动物模型评价的研究进展
- Author:
Ziyue ZHU
1
;
Lu WANG
;
Junpeng YAO
;
Huilin LIU
;
Yanqiu LI
;
Ying LI
;
Wei ZHANG
Author Information
1. 成都中医药大学针灸推拿学院,成都 610075
- Keywords:
diabetic peripheral neuropathy;
animal model;
evaluation;
research progress;
review
- From:
Chinese Journal of Comparative Medicine
2024;34(1):139-145,157
- CountryChina
- Language:Chinese
-
Abstract:
Diabetic peripheral neuropathy is a common diabetic complication.Presently,our understanding of its pathogenesis is incomplete,and there are no effective treatment options.In-depth research requires the use of animal experiments.The criteria for modeling success and the evaluation method for peripheral nerve function recovery are critical for carrying out animal experiments into type 2 diabetic peripheral neuropathy.However,but there has been a lack of systematic interrogation and analysis of the evaluation method used with type 2 diabetic peripheral neuropathy models.Therefore,the author reviewed the recent data,summarized and analyzed the evaluation method used for animal models of type 2 diabetic peripheral neuropathy of small and large nerve fibers,and proposed future directions for development,providing a reference for related research.
