Research progress on modeling methods and evaluation indexes of kidney injury in zebrafish
10.3969/j.issn.1671-7856.2023.12.019
- VernacularTitle:斑马鱼肾损伤造模方法及评价指标的研究进展
- Author:
Ailin LAN
1
;
Chunhua HUANG
;
Ming XIA
;
Maojuan LI
;
Siqi WANG
;
Didong LOU
Author Information
1. 贵州省法医中药毒理学特色重点实验室,贵州中医药大学司法鉴定所,贵阳 550000
- Keywords:
zebrafish;
kidney injury;
animal models
- From:
Chinese Journal of Comparative Medicine
2023;33(12):123-126
- CountryChina
- Language:Chinese
-
Abstract:
Kidneys filter bloodand regulate fluid and electrolyte balances.However,the kidney is susceptible to toxicity of various compounds,Resulting in renal damage.Hence,prevention and treatment of renal injury is a hot research topic.Zebrafish is an ideal animal model,because it is closely related to humans in terms of morphology,physiology,and kidney functions and its response to compounds.In this article,we review the method and evaluation indexes of zebrafish kidney injury modeling.
