Research progress on the construction and evaluation indicators of skin-wound animal models based on physical methods
10.3969/j.issn.1005-4847.2024.01.015
- VernacularTitle:基于物理方法的皮肤创伤动物模型构建及评价指标研究进展
- Author:
Xue OU
1
;
Zhijie YU
;
Yao HE
;
Xiaoyuan ZHENG
Author Information
1. 重庆大学医学院,重庆 400030
- Keywords:
physical method;
skin wounds;
construction of models;
evaluation indicators
- From:
Acta Laboratorium Animalis Scientia Sinica
2024;32(1):128-138
- CountryChina
- Language:Chinese
-
Abstract:
Skin wounds are global public problems,especially in terms of the difficult healing of chronic wounds,which may seriously affect patients'lives.Most skin-wound animal models are currently established by physical method,and different animal models have different biological characteristics.This review therefore classifies mouse,rat,and other animal models of skin wounds according to the literature,summarizes and analyzes the construction of skin-wound animal models based on physical method and evaluation indicators,and considers the advantages and disadvantages of different animal models,to provide a basis for the rational construction of skin-wound animal models and drug research and development.
