Research progress on experimental models of idiopathic pulmonary fibrosis

VernacularTitle:特发性肺纤维化实验模型研究进展
Author: Zhihui LI ¹ ; Xueqing YU ; Shuguang YANG ; Ningxia YU ; Danyang ZANG
Author Information

1. 河南中医药大学,郑州 450046
Keywords: idiopathic pulmonary fibrosis; acute exacerbation; experimental model; traditional Chinese medicine model
From: Acta Laboratorium Animalis Scientia Sinica 2024;32(1):118-127
CountryChina
Language:Chinese
Abstract: Idiopathic pulmonary fibrosis(IPF)is a chronic,progressive interstitial lung disease.IPF incidence is increasing yearly with high mortality and poor prognoses.At present,IPF pathogenesis remains unclear,and its treatments are limited.The experimental model is important to further study IPF pathogenesis and explore effective preventive and therapeutic measures.In recent years,its modeling method have been continuously developed and optimized.This study summarizes the establishment method and research progress of IPF experimental models in recent years to provide ideas and references for preclinical research to select appropriate experimental models.