Research progress in aging rodent models
10.3969/j.issn.1005-4847.2023.12.011
- VernacularTitle:啮齿类动物衰老模型研究新进展
- Author:
Xuechan LI
1
;
Le HAN
;
Xuewen WANG
;
Lijun LIU
;
Jianjun WU
;
Jing WANG
Author Information
1. 甘肃中医药大学公共卫生学院,兰州 730000
- Keywords:
aging model;
rodents;
mechanism
- From:
Acta Laboratorium Animalis Scientia Sinica
2023;31(12):1605-1609
- CountryChina
- Language:Chinese
-
Abstract:
Aging is a process of degenerative change that occurs as a result of time-related accumulation,associated with age-related diseases.Understanding the causes and mechanisms of aging and finding drugs that can effectively delay aging and prevent and cure age-related diseases currently present a great challenge for humans.Aging animal models thus represent an important tool in aging research,and various aging animal models have been created using different aging mechanisms.These different models having specific advantages and disadvantages,making them suitable for different research purposes.This review considers aging rodent models to provide information for aging research.