Skin injury around enterostomy cured by allogeneic platelet-rich plasma: a report of two cases
10.13303/j.cjbt.issn.1004549x.2024.02.014
- VernacularTitle:同种异体富血小板血浆治疗肠造口周围皮肤损伤的探讨
- Author:
Honglin YAO
1
;
Qing QI
2
;
Shujun WANG
2
;
Shuo SHEN
1
;
Jianfeng LUAN
2
;
Xianghong YE
1
Author Information
1. Research Institute of General Surgery, Eastern Theater Command General Hospital, Nanjing 210002, China
2. Department of Blood Transfusion, Eastern Theater Command General Hospital, Nanjing 210002, China
- Publication Type:Journal Article
- Keywords:
platelet-rich plasma(PRP);
enterostomy;
skin injury around enterostomy
- From:
Chinese Journal of Blood Transfusion
2024;37(2):209-213
- CountryChina
- Language:Chinese
-
Abstract:
【Objective】 To investigate the feasibility of allogeneic platelet-rich plasma (PRP) for the treatment of skin injury around enterostomy. 【Methods】 The treatment process by PRP of 2 patients with skin injury around enterostomy was analyzed, and the PRP for each patient was tested with platelet count, bacteria and 5 growth factors. The clinical efficacy of enteral nutrition support therapy combined with allogeneic PRP was explored through analyzing treatment key points and literature review. 【Results】 After cleaning the skin around enterostomy, the patients were treated with PRP once daily for 5 days, adjusted to once every other day, and cure was achieved at 15 and 18 days, respectively. 【Conclusion】 Allogeneic PRP is a safe and effective treatment to promote skin injury around enterostomy regeneration in a short time, which can provide a new perspective for clinical.